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Genentech will take a $25-million charge against...

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Genentech will take a $25-million charge against its fourth-quarter earnings to cover the cost of destroying its heart attack drug TPA that remains unsold past its expiration date . . . AMC Entertainment said it sold its British movie theaters for about $98 million to a joint venture owned by Tele-Communications, MCA and Gulf & Western’s Paramount Pictures . . . Sanyo Electric Co. of Japan has established Sanyo North America Corp., its first North American headquarters, in Manhattan, with branch offices to be located in unspecified sites in California .

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