David Bowie, Trent Reznor Nailing Down Joint Tour : The veteran rocker’s fall pairing with Nine Inch Nails may hit two Southland sites.

Move over, Neil Young and Pearl Jam. Another cross-generational teaming of a ‘70s rock icon and a ‘90s titan is completing plans for a U.S. tour: David Bowie and Nine Inch Nails.

The pairing is a natural.

Like Young, Bowie is often cited by young rockers as a seminal inspiration, thanks to his liberating personas (notably Ziggy Stardust) and his bold musical explorations.

Nine Inch Nails’ Trent Reznor has frequently said in interviews that Bowie’s albums, especially his 1977 “Low” collaboration with producer-musician Brian Eno, have been key influences on him.

Representatives of Bowie and Reznor would not comment until details are in place, but Pop Eye has confirmed that the trek is scheduled for mid-September through October, with dates expected at the Irvine Meadows Amphitheatre and probably one Los Angeles site. Bowie will officially be the headliner, though he and Reznor are expected to appear on stage together, perhaps for an encore.

The tour, which will coincide with the release of “Outside,” Bowie’s first album under a new deal with Virgin Records, was conceived by William Morris agent Alison Hamamura and will be produced by Toronto-based CPI, the firm that oversees the Rolling Stones’ tours and handled Bowie’s last jaunt, the 1990 “Sound + Vision” greatest-hits shows.

But will the joint venture have box-office appeal?

Though Bowie played stadiums the last time around, many industry observers wonder whether he will still be a major draw given his lack of significant chart or alternative radio presence in recent years.

And will his older fans be scared off by the aggressive, brutal music and imagery of Nine Inch Nails?

“Any time you mix widely divergent audiences there’s a potential for it not to go well,” says Gary Bongiovanni, editor of the concert industry trade magazine Pollstar. “Certainly I don’t know that a lot of Bowie’s older fans will be ready for Nine Inch Nails. But I expect it will work fine. Nine Inch Nails fans probably don’t care for Bowie’s disco days, but his Ziggy Stardust-era music isn’t that far from what they would embrace.”

Clearly, then, Bowie stands to benefit more.

“It’s a great move for Bowie,” says Craig Marks, music editor of Spin magazine. “It doesn’t seem like Reznor is doing this as a favor to Bowie, but he’s actually extending the hand of youth to him.”

And what will Reznor get in return? Apparently the thrill of touring with one of his idols. That’s the consensus speculation for the rationale for Reznor’s being lured back to the road after spending much of the past year and a half on tour.

“[Reznor] doesn’t need to do it for commercial reasons,” says Marks. “So I’m sure he’s doing it for homage reasons, which are extremely genuine.”