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Some officials now say MPX elimination unlikely in U.S.

A physician assistant prepares a syringe with the MPX vaccine.
A physician assistant prepares a syringe with the MPX vaccine. The disease’s spread is slowing in the U.S. but the virus is unlikely to be eliminated, the Centers for Disease Control and Prevention said.
(Mary Altaffer / Associated Press)
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Some U.S. health officials are conceding that monkeypox, or MPX, is probably not going away anytime soon.

The disease’s spread is slowing but the virus is so widespread that elimination is unlikely, the Centers for Disease Control and Prevention said. That conclusion was in a recent CDC report, and echoed Friday by Marc Lipsitch, director of science in the agency’s disease-forecasting center.

Editor's Note:

In light of widespread concerns that the name “monkeypox” is racist and stigmatizing, the World Health Organization has renamed the disease “mpox.”

Lipsitch hesitated to say MPX is permanently here to stay, but he said it stands to be a continuing threat for the next few years.

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“It’s in many geographic locations within the country” as well as in other countries, Lipsitch said. “There’s no clear path in our mind to complete elimination domestically.”

The virus that causes the disease has mainly spread among gay and bisexual men, though health officials continue to stress that anyone can be infected. It’s important that people at risk take steps to prevent spread and that vaccination efforts continue, Lipsitch said.

Experts around the world have pledged to change the disease’s name to something that doesn’t carry the weight of stigma. But tossing out the old term is easier than deciding on a new one.

Aug. 26, 2022

The CDC report contained some good news: The U.S. outbreak seems to have peaked in early August. The average number of daily cases being reported — fewer than 150 — is about a third what it was reported in the middle of the summer, and officials expect the decline will continue for at least the next several weeks.

Lipsitch attributed the good news to increasing vaccinations, cautious behavior by people at risk and infection-derived immunity in the highest-risk populations.

Dr. Tom Inglesby, director of the Johns Hopkins Center for Health Security, agreed that it’s unlikely that spread of MPX will stop in the U.S. anytime soon, but he said it’s still possible in the long term.

If domestic transmission were stopped, infections may still continue if people catch the virus while traveling internationally, he said. But the declining cases make it seem as though “we’ve turned a real corner.”

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“The efforts underway are succeeding, and should be continued, if not intensified,” he said.

Vaccines for MPX are now easier to get. Los Angeles County has expanded eligibility, and you can get a shot at one of several walk-up clinics.

Sept. 20, 2022

With case numbers going down, this is a good time for local health departments to take a new stab at doing intensive contact tracing to try to stop chains of transmission, he said.

MPX is endemic in parts of Africa, where people have been infected through bites from rodents or small animals, but it wasn’t considered a disease that spreads easily among people until May, when infections emerged in Europe and the U.S.

There have been more than 67,000 cases reported in countries that have not historically seen MPX. The U.S. has the most infections of any country — more than 25,600. One U.S. death has been attributed to MPX. The victim was a resident of Los Angeles County and was “severely immunocompromised,” local health officials said.

More than 97% of U.S. cases are men. The vast majority have been men who reported recent sexual contact with other men.

Though cases have been declining, the proportion of new cases that have information about recent sexual contact is also down, officials said. That’s causing a growing blind spot about how the virus may be spreading, Lipsitch noted.

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